Are PCR tests the key?
I have been looking up what pcr tests actually are because I constantly hear that they are the ones that are being used to diagnose as cases.
From my cursory layman's research, what the test does is basically lets you focus in on a specific molecule or whatever with higher and higher fidelity each time you rerun the test.
In other words, once they take a piece of your DNA, they run it through a PCR test dozens of times and each time they do, the virus comes more and more into view, up to the point where 60 test runs will yield 100% "infection" rates.
The standardization of cycles that should
be done, however, is not clear and I have heard (but not verified)¹ that the WHO recommends 45 cycles which has been the subject of criticism from doctors for yielding too many false positives, or "asymptomatic individuals".
According to a New York Times
Any test with a cycle threshold above 35 is too sensitive, agreed Juliet Morrison, a virologist at the University of California, Riverside. “I’m shocked that people would think that 40 could represent a positive,” she said.
The point of the test is not to be utilized as a diagnostic tool for doctors, but as a way to quantify precisely how prevalent a particular genetic query is in a sample as well as get the molecule to a measurable size for research.
There is a big difference and the understandable ignorance of this topic is how they are able to make case numbers seem like they are rising
The inventor of the PCR test, Nobel Laureate Kary Mullins, has said if you "use the PCR test well, you can find almost anything in any body"
(time stamp 2:30).
He goes on to say that "if you can amplify one single molecule up to something that you can really measure, there's very few molecules that you don't have at least one single one of"
These tests are to the foundation to the state line that there is still a pandemic to justify ticketing and/or arresting people for not wearing masks out in public around the world. This, of course, gives the state the precedent for new powers but also gives blank checks to pharmaceutical companies and vaccine producers that, I'm sure just by chance, have been absolved of any and all liability from vaccine liability claims.
Thermal cycling was performed at 55°C for 10 min for reverse transcription, followed by 95°C for 3 min and then 45 cycles of 95°C for 15 s, 58°C for 30 s.
submitted by FakePimple
Quick review of Beyerdynamic TYGR 300 R from a non-audiophile perspective
I was originally using the Corsair Void Pro USB headset, but as I recently invested in a proper mic, boom arm and audio interface, I thought I'd switch out my headset for a pair of higher fidelity headphones as I didn't need the mic anymore, which would function well for both gaming and listening to music and would hopefully sound better than my headset. I eventually settled on the Beyerdynamic TYGR 300R, and I've been using them for a couple of days.
They didn't initially feel quite as comfy as my corsair headset, but I've mostly grown used to it now. They clamp a lot harder (the corsair headphones had essentially no clamping force so after using those for a couple of years it was quite a contrast) and the ear cups aren't quite as deep, but I mostly forget I'm wearing them now and they are still very comfy now they've adjusted to my head. My only gripe is my ears sometimes touch the padding on the inside next to the drivers themselves, because of the not so deep ear cups, but these are replaceable anyway.
When I first tested them listening to music against my Corsair headphones, I didn't notice a huge, immediate difference and felt a twang of disappointment. But after switching back and forth, I started noticing all these details in songs I'd never noticed before, which the corsair headphones drowned out. I could pick out individual sounds far easier from different directions in my ears and each of those sounds were far more clear. The Corsair headphones tried to make up for lack of detail by crudely amplifying certain frequencies, particularly the lower frequencies. Everything sounded just a bit less 'muddy' all round on my Beyerdynamics. I could listen to music and play games and get really immersed and enjoy the sounds rather than the sounds kinda just being there. I find chill, lofi beats to be the best thing to listen to with these headphones, which I wasn't as interested in listening to before because all I could really make out was the main beat itself, rather than all the other sounds and instruments typically present in those kind of songs.
So yeah, that's my quick review for anyone looking to make a switch like I did. What are other peoples thoughts?
submitted by BentYoda